E-ISSN 2250-0944 | ISSN 2250-1150
 

- 


Antiurolithiatic Activity Studies of Momordica charantia Linn. Fruits

Biren N. Shah, Khodidas D. Raiyani*, D. C. Modi.

Cited by (1)

Abstract
In the indigenous system of medicine, the fruits of Momordica charantia Linn. (Family- Cucurbitaceae) are reported to be useful in the treatment of urinary stones. Hence, in the present study the fruits of Momordica charantia Linn. have been selected for their antiurolithiatic activity on experimentally induced urolithiatic rats. Antiurolithiatic activity of fruit extract of M. charantia Linn. was carried out on ethylene glycol (0.75% v/v) induced urolithiasis in rats. Treatment with Aqueous Extract (200mg/kg, p.o) and Alcoholic Extract (250mg/kg, p.o) of fruits of M. charantia Linn. significantly lowered (P<0.001) the increased levels of oxalate, calcium and phosphate in urine and also significantly reduced (P<0.001) their retention in kidney. The treatment with Aqueous extract and Alcoholic extract of fruits significantly (P<0.001) lowered the elevated serum levels of Blood urea nitrogen, creatinine and uric acid in both regimens. The histopathological study of the kidney also supported the above results. The results were comparable to that of standard drug (Cystone). The presented data indicate that administration of M. charantia Linn. fruits extracts to rats with experimentally-induced urolithiasis reduced and also prevented the formation of urinary stones, supporting folk information regarding antiurolithiatic activity of the plant. The reduction in the stone forming constituents in urine and renal tissue brought about by M. charantia Linn. could contribute to its antiurolithiatic property.

Key words: Momordica charantia Linn., Urolithiasis, Ethylene glycol, calcium oxalate.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Biren N. Shah
Articles by Khodidas D. Raiyani*
Articles by D. C. Modi
on Google
on Google Scholar


This Article Cited By the following articles

Automatic preprocessing of blood cells using edge detectors for the detection of leukemia
International Journal of Pharmaceutical Research 2019; 11(1): .

1
 
How to Cite this Article
Pubmed Style

Biren N. Shah, Khodidas D. Raiyani , D. C. Modi. Antiurolithiatic Activity Studies of Momordica charantia Linn. Fruits. IJPRT. 2011; 1(1): 06-11. doi:10.31838/ijprt/01.01.02


Web Style

Biren N. Shah, Khodidas D. Raiyani , D. C. Modi. Antiurolithiatic Activity Studies of Momordica charantia Linn. Fruits. https://www.ijprt.org/?mno=302643671 [Access: June 25, 2022]. doi:10.31838/ijprt/01.01.02


AMA (American Medical Association) Style

Biren N. Shah, Khodidas D. Raiyani , D. C. Modi. Antiurolithiatic Activity Studies of Momordica charantia Linn. Fruits. IJPRT. 2011; 1(1): 06-11. doi:10.31838/ijprt/01.01.02



Vancouver/ICMJE Style

Biren N. Shah, Khodidas D. Raiyani , D. C. Modi. Antiurolithiatic Activity Studies of Momordica charantia Linn. Fruits. IJPRT. (2011), [cited June 25, 2022]; 1(1): 06-11. doi:10.31838/ijprt/01.01.02



Harvard Style

Biren N. Shah, Khodidas D. Raiyani , D. C. Modi (2011) Antiurolithiatic Activity Studies of Momordica charantia Linn. Fruits. IJPRT, 1 (1), 06-11. doi:10.31838/ijprt/01.01.02



Turabian Style

Biren N. Shah, Khodidas D. Raiyani , D. C. Modi. 2011. Antiurolithiatic Activity Studies of Momordica charantia Linn. Fruits. International Journal of Pharmacy Research & Technology, 1 (1), 06-11. doi:10.31838/ijprt/01.01.02



Chicago Style

Biren N. Shah, Khodidas D. Raiyani , D. C. Modi. "Antiurolithiatic Activity Studies of Momordica charantia Linn. Fruits." International Journal of Pharmacy Research & Technology 1 (2011), 06-11. doi:10.31838/ijprt/01.01.02



MLA (The Modern Language Association) Style

Biren N. Shah, Khodidas D. Raiyani , D. C. Modi. "Antiurolithiatic Activity Studies of Momordica charantia Linn. Fruits." International Journal of Pharmacy Research & Technology 1.1 (2011), 06-11. Print. doi:10.31838/ijprt/01.01.02



APA (American Psychological Association) Style

Biren N. Shah, Khodidas D. Raiyani , D. C. Modi (2011) Antiurolithiatic Activity Studies of Momordica charantia Linn. Fruits. International Journal of Pharmacy Research & Technology, 1 (1), 06-11. doi:10.31838/ijprt/01.01.02





Most Viewed Articles
  • Stability Indicating HPLC Method for Simultaneous Estimation of Nicotinamide and Salicylic Acid
    FALGUNI TANDEL, PRATIMA MORE
    IJPRT. 2018; 8(2): 43-47
    » Abstract » doi: 10.31838/ijprt/08.02.05

  • FORMULATION AND EVALUATION OF NANO PARTICULATE DRUG DELIVERY SYSTEM FOR AN EFFECTIVE TREATMENT OF ACNE
    ISHRAT S. CHHOWALA, DEVARSHI MADHUBHAI JANI, DR ABHAY DHARAMSI, DR. GAJANAN SHINDHE, DR. RAKESH PATEL.
    IJPRT. 2018; 8(2): 14-26
    » Abstract » doi: 10.31838/ijprt/08.02.02

  • Antimicrobial activities, antioxidant and phytochemical analysis of methanol and aqueous leaf extract of Phyllathus muellerianus (KUNTZ) Exell
    FRED COOLBORN AKHARAIYI* ,ABAYOMI OLABANJO DINA
    IJPRT. 2018; 8(1): 29-38
    » Abstract » doi: 10.31838/ijprt/08.01.04

  • Pharmacovigilance system and the future challenges in India-A Perspective
    *SANDHYA JAIN*, 1DR VIKAS JAIN, 2RADHA SHARMA
    IJPRT. 2018; 8(2): 27-31
    » Abstract » doi: 10.31838/ijprt/08.02.03

  • Piperine : A Bioenhancer
    Amar Singh*, Amar Deep
    IJPRT. 2011; 1(1): 1-5
    » Abstract » doi: 10.31838/ijprt/01.01.01

  • Most Downloaded
  • RELEASE KINETICS – CONCEPTS AND APPLICATIONS
    M. PADMAA PAARAKH , PREETHY ANI JOSE* , CM SETTY , G.V. PETER CHRISTOPER
    IJPRT. 2018; 8(1): 12-20
    » Abstract » doi: 10.31838/ijprt/08.01.02

  • A case report on sympneumonic effusion
    Sandeep Akkam, Pooja dasari, Nandini Thota,
    IJPRT. 2021; 11(2): 17-18
    » Abstract » doi: 10.31838/ijprt/11.02.02

  • FORMULATION AND EVALUATION OF ACTIVATED CHARCOAL PEEL OFF MASK
    SWETA V.KULKARNI*, DR.ARUN K.GUPTA, SHUBHAM BHAWSAR
    IJPRT. 2019; 9(2): 44-48
    » Abstract » doi: 10.31838/ijprt/09.02.06

  • FORMULATION AND EVALUATION OF NANO PARTICULATE DRUG DELIVERY SYSTEM FOR AN EFFECTIVE TREATMENT OF ACNE
    ISHRAT S. CHHOWALA, DEVARSHI MADHUBHAI JANI, DR ABHAY DHARAMSI, DR. GAJANAN SHINDHE, DR. RAKESH PATEL.
    IJPRT. 2018; 8(2): 14-26
    » Abstract » doi: 10.31838/ijprt/08.02.02

  • Medicinal vegetal use by traditional healers in Ekiti State of Nigeria for diabetes treatment
    AKHARAIYI, FRED COOLBORN , ADEROBA ADEYEMI ADEGBEMISIPO
    IJPRT. 2018; 8(1): 21-28
    » Abstract » doi: 10.31838/ijprt/08.01.03

  • Most Cited Articles
  • Piperine : A Bioenhancer
    Amar Singh*, Amar Deep
    IJPRT. 2011; 1(1): 1-5
    » Abstract » doi: 10.31838/ijprt/01.01.01
    Cited : 5 times [Click to see citing articles]

  • Biodiversity and conservation Ferns Diversity in different forests of Dehradun district
    CHHAYA SINGH, BRIJESH KUMAR, ANJU RANI, KAMLA DHYANI, RAJ SINGH
    IJPRT. 2017; 7(2): 01-07
    » Abstract » doi: 10.31838/ijprt/07.02.01
    Cited : 3 times [Click to see citing articles]

  • Stability Indicating HPLC Method for Simultaneous Estimation of Nicotinamide and Salicylic Acid
    FALGUNI TANDEL, PRATIMA MORE
    IJPRT. 2018; 8(2): 43-47
    » Abstract » doi: 10.31838/ijprt/08.02.05
    Cited : 3 times [Click to see citing articles]

  • A Preliminary Investigation of Moringa Oleifera Lam Gum As a Pharmaceutical Excipient
    Dhiren P Shah*, Vineet C Jain, Hitesh P Dalvadi, Vinod D Ramani, Kajal G Patel, Mahesh G Saralai, Girish K Jani
    IJPRT. 2011; 1(1): 12-16
    » Abstract » doi: 10.31838/ijprt/01.01.03
    Cited : 2 times [Click to see citing articles]

  • EFFECT OF SEED EXTRACTS OF Elettaria cardamomum ON CALCIUM OXALATE CRYSTALLIZATION
    Manish A. Patel, Paras K. Patel, Dr. Avinash K Seth
    IJPRT. 2011; 1(1): 21-25
    » Abstract » doi: 10.31838/ijprt/01.01.05
    Cited : 2 times [Click to see citing articles]