E-ISSN 2250-0944 | ISSN 2250-1150
 

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Wound-healing activity of ethanolic and aqueous extracts of Ficus sarmentosa bark

ASHISH DIMRI*, DR.ARVIND NEGI, DR.AMIT SEMWAL, DR. (PROF) NARDEV SINGH.

Abstract
Wound healing is the process of repair that follows injury to the skin and other soft tissues. Following injury, an
inflammatory response occurs and the cells below the dermis (the deepest skin layer) begin to increase collagen
(connective tissue) production. Later, the epithelial tissue (the outer skin) is regenerated. There are three stages to the
process of wound healing: inflammation, proliferation, and remodeling. Traditionally, Ficus sarmentosa is used for wound
healing. Since no detailed scientific data are available regarding the wound-healing activity of F. sarmentosa, the present
study was designed to explore the same. The wound-healing efficacy of ethanolic and aqueous extracts of F.
sarmentosa was evaluated in excision and incision wound models. The parameters studied include rate of wound
contraction, period of complete epithelialization, and tensile strength of incision wound. Student's t test was used to
analyze the results obtained from the present study and P<0.05 was considered significant. Both the ethanolic and
aqueous extracts of F. sarmentosa were found to possess significant wound-healing activity, which was evidenced by
decrease in the period of epithelialization, increase in the rate of wound contraction and skin-breaking strength. The
present study has demonstrated that the ethanolic and aqueous extracts of F. sarmentosa have properties that render
them capable of promoting accelerated wound-healing activity compared with placebo control

Key words: Excision wound model, F. sarmentosa, incision wound model, tensile strength


 
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How to Cite this Article
Pubmed Style

DIMRI A, NEGI D, SEMWAL D, SINGH D(N. Wound-healing activity of ethanolic and aqueous extracts of Ficus sarmentosa bark. IJPRT. 2019; 9(1): 38-42. doi:10.31838/ijprt/09.01.05


Web Style

DIMRI A, NEGI D, SEMWAL D, SINGH D(N. Wound-healing activity of ethanolic and aqueous extracts of Ficus sarmentosa bark. https://www.ijprt.org/?mno=302643967 [Access: June 25, 2022]. doi:10.31838/ijprt/09.01.05


AMA (American Medical Association) Style

DIMRI A, NEGI D, SEMWAL D, SINGH D(N. Wound-healing activity of ethanolic and aqueous extracts of Ficus sarmentosa bark. IJPRT. 2019; 9(1): 38-42. doi:10.31838/ijprt/09.01.05



Vancouver/ICMJE Style

DIMRI A, NEGI D, SEMWAL D, SINGH D(N. Wound-healing activity of ethanolic and aqueous extracts of Ficus sarmentosa bark. IJPRT. (2019), [cited June 25, 2022]; 9(1): 38-42. doi:10.31838/ijprt/09.01.05



Harvard Style

DIMRI, A., NEGI, . D., SEMWAL, . D. & SINGH, . D. (. N. (2019) Wound-healing activity of ethanolic and aqueous extracts of Ficus sarmentosa bark. IJPRT, 9 (1), 38-42. doi:10.31838/ijprt/09.01.05



Turabian Style

DIMRI, ASHISH, DR.ARVIND NEGI, DR.AMIT SEMWAL, and DR. (PROF) NARDEV SINGH. 2019. Wound-healing activity of ethanolic and aqueous extracts of Ficus sarmentosa bark. International Journal of Pharmacy Research & Technology, 9 (1), 38-42. doi:10.31838/ijprt/09.01.05



Chicago Style

DIMRI, ASHISH, DR.ARVIND NEGI, DR.AMIT SEMWAL, and DR. (PROF) NARDEV SINGH. "Wound-healing activity of ethanolic and aqueous extracts of Ficus sarmentosa bark." International Journal of Pharmacy Research & Technology 9 (2019), 38-42. doi:10.31838/ijprt/09.01.05



MLA (The Modern Language Association) Style

DIMRI, ASHISH, DR.ARVIND NEGI, DR.AMIT SEMWAL, and DR. (PROF) NARDEV SINGH. "Wound-healing activity of ethanolic and aqueous extracts of Ficus sarmentosa bark." International Journal of Pharmacy Research & Technology 9.1 (2019), 38-42. Print. doi:10.31838/ijprt/09.01.05



APA (American Psychological Association) Style

DIMRI, A., NEGI, . D., SEMWAL, . D. & SINGH, . D. (. N. (2019) Wound-healing activity of ethanolic and aqueous extracts of Ficus sarmentosa bark. International Journal of Pharmacy Research & Technology, 9 (1), 38-42. doi:10.31838/ijprt/09.01.05





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