https://ijprt.org/index.php/pub <p><strong>International Journal of Pharmacy Research &amp; Technology (IJPRT) </strong>an International Journal of Pharmaceutical Research &amp; Technology <strong>(ISSN - 2250–0944) (P-ISSN 2250-1150) NLM ID: NLM ID:<a href="https://www.ncbi.nlm.nih.gov/nlmcatalog/?term=101751838">101751838</a> </strong> (An official publication of <em>Advanced Scientific Research</em>) is established in the year 2009. </p> <p>The aim of the ​<strong>International Journal of Pharmacy Research &amp; Technology (IJPRT) </strong>is to become an effective medium for inspiring the researchers to bring out their contributions in the form of research papers, articles, case studies, review articles and in the fields of Pharmacy, Medical sciences and Science and technology. The dissemination would thus help the industries, professional organisations to adopt and apply the information for creating new knowledge and enterprise. The publication would also help in enhancing awareness about the need to become research minded.</p> <p>All articles published in the journal will be freely available to scientific researchers to all over the globe. We will be making sincere efforts to promote our journal across the world in various ways. It is hoped that this journal will act as a common platform for researchers to pursue their objectives.</p> IJPRT en-US International Journal of Pharmacy Research & Technology (IJPRT) 2250-1150 https://ijprt.org/index.php/pub/article/view/602 <p>A randomized prospective study evaluated the educational impact of a flipped-classroom (FC)model versus conventional didactic teaching in a 4-week neurology clerkship among 104 medicalstudents. Participants were randomized to FC (n = 49)—comprising pre-class videos, readings</p> Muhammad Nadeem Shafique, Bushra Owais Muhammad Yawar Khan, Saleem Adil, Attia Sheikh, Asma Siddiqui, Farah Naz Tahir Copyright (c) 2025 https://creativecommons.org/licenses/by/4.0 2025-06-16 2025-06-16 15 2 1 6 https://ijprt.org/index.php/pub/article/view/603 <p>A prospective randomized controlled trial evaluated long-term efficacy and varicose veinrecurrence in adults treated with endovenous laser therapy (EVLT; n = 100) versus surgicalstripping (SS; n = 100) of the great saphenous</p> Devishi Sarin, Muhammad Tariq Bashir, Inayat Husain Anjum Muhammad Asif, Syed Irfan Raza Arif, Junaid Hassan Copyright (c) 2025 https://creativecommons.org/licenses/by/4.0 2025-06-16 2025-06-16 15 2 7 12 https://ijprt.org/index.php/pub/article/view/604 <p>A cross-sectional analysis assessed the diagnostic accuracy of fecal calprotectin (FC) in 200ulcerative colitis (UC) patients undergoing surveillance colonoscopy. FC levels were comparedwith Mayo endoscopic subscore</p> Zahoor Ahmed Shah, Syed Osama Talat Jalal Khan, Abdul Sadiq, Shahzad Latif, Syed Ehsanullah, Farah Naz Tahir Copyright (c) 2025 https://creativecommons.org/licenses/by/4.0 2025-06-16 2025-06-16 15 2 13 17 https://ijprt.org/index.php/pub/article/view/605 <p>In a prospective cohort of 400 elderly patients (≥70 years) with symptomatic atrial fibrillation(AF), 200 underwent catheter ablation</p> Zahoor Ahmed Shah, Hafiz Muhammad Shafique, Atif Imran, Zain ul Abideen, Asim Saif Ahmad, Muhammad Zarrar Arif Butt, Farah Naz Tahir Copyright (c) 2025 https://creativecommons.org/licenses/by/4.0 2025-06-16 2025-06-16 15 2 18 22 https://ijprt.org/index.php/pub/article/view/626 <p>Parkinson's disease (PD) is a neurodegenerative disorder that results in the gradual death of dopaminergic neurons in the human brain, leading to both motor impairment and a variety of non-motor symptoms. Pyrazoline is a heterocyclic compound known for its pharmacological spectrum and anti-inflammatory, antioxidant, and neuroprotective properties. Recent studies have highlighted its potential in modulating key pathways involved in PD, such as oxidative stress, mitochondrial dysfunction, and neuroinflammation, all of which are central to the progression of Parkinson's disease. These derivatives have shown promise in preclinical models by mitigating neuronal damage and preserving motor function, making them attractive candidates for further research. This review included the background on Parkinson’s disease, current treatment options, common synthetic route of Pyrazoline ring, current medicines used for the treatment of PD, and recent studies done on Pyrazoline ring as anti-Parkinson's.</p> Bidhyut Kumar Dubey Jyoti Anurag Avinash Chandra Tripathi Mohini Chaurasia Mohammad Asif Copyright (c) 2025 Authors https://creativecommons.org/licenses/by/4.0 2025-06-20 2025-06-20 15 2 23 35 https://ijprt.org/index.php/pub/article/view/634 <p>Antimicrobial resistance in urinary tract infections (UTIs) poses a major challenge to effectivetreatment across age groups. This cross-sectional study examined resistance patterns in 240patients (120 pediatric, age 1–17; 120 adult, age 18–75) presenting with culture-confirmed UTIs.</p> Aqsa Rashid, Jalal Khan, Zahoor Ahmed Shah, Khowla Rabbani, Tahir Shahzad Nawaz Babar, Syed Hasan Farooq, Farah Naz Tahir Copyright (c) 2025 https://creativecommons.org/licenses/by/4.0 2025-06-24 2025-06-24 15 2 36 42 https://ijprt.org/index.php/pub/article/view/635 <p>A prospective randomized controlled trial compared clinical outcomes of resorbable versus <br>titanium plate fixation in mandibular fractures among 100 adult patients (aged 18–60 years) with <br>symphyseal or angle fractures</p> Rabia Naseer, Abdul Manan Shahid, Palwasha Ishaque, Zainab Khalid, Muhammad Azeem Khan, Amna Hassan, Farah Naz Tahir Copyright (c) 2025 https://creativecommons.org/licenses/by/4.0 2025-06-24 2025-06-24 15 2 43 49 https://ijprt.org/index.php/pub/article/view/636 <p>A cross-sectional forensic study evaluated the utility of biochemical markers (serum surfactant D,NT-proBNP, D-dimer) and diatom quantification for confirming drowning as the cause of death.Eighty postmortem cases were investigated&nbsp;</p> Ume Kalsoom Asiya Fazal Farhat Sultana, Wasiq Ahmed Mansoora Mirza, Muhammad Anwar Sibtain Fazli Copyright (c) 2025 https://creativecommons.org/licenses/by/4.0 2025-06-24 2025-06-24 15 2 50 54 https://ijprt.org/index.php/pub/article/view/637 <p>A randomized controlled trial evaluated 180 adults undergoing elective distal-limb orthopaedicsurgery under regional anaesthesia (RA) with sedation (n=90) versus RA without sedation (n=90).Primary outcomes were patient satisfaction</p> Furqan Akram, Fareed Naeem, Usman Zeeshan³, Gul Sher, Mohammad Baqir Ali Khan, Ali Kashif, Farah Naz Tahir Copyright (c) 2025 https://creativecommons.org/licenses/by/4.0 2025-06-24 2025-06-24 15 2 55 59 https://ijprt.org/index.php/pub/article/view/638 <p>Emerging evidence implicates adiponectin and leptin in glucose homeostasis and metabolicregulation among individuals with type 2 diabetes mellitus (T2DM). The present experimentalstudy investigated their association with glycemic control in a cross-sectional cohort of 120 adult</p> Farhan Tariq, Jalal Khan, Mohammad Abid, Tashfeen Ikram Bushra Hussain, Syed Ehsan ullah, Farah Naz Tahir Copyright (c) 2025 https://creativecommons.org/licenses/by/4.0 2025-06-24 2025-06-24 15 2 60 66