Mitochondrial Dynamics and Oxidative Stress-Driven Apoptosis:  Cardiovascular and renal Implications from an In Vitro Study

Ali Saqlain Haider, Reja Akram, Irfana Hassan, Muhammad Ahmad Raza Butt, Yamna Fatima, Khadija Kiran

Mitochondrial Dynamics and Oxidative Stress-Driven Apoptosis: Cardiovascular and renal Implications from an In Vitro Study

Authors

Ali Saqlain Haider, Reja Akram, Irfana Hassan, Muhammad Ahmad Raza Butt, Yamna Fatima, Khadija Kiran

Keywords:

mitochondrial dynamics, oxidative stress, apoptosis

Abstract

Mitochondrial dysfunction is increasingly recognized as a driver of cell death incardiovascular and renal pathologies. This in vitro experimental study aimed to examine howperturbations in mitochondrial dynamics contribute to oxidative stress–induced apoptosis in cardiomyocytes and renal tubular epithelial cells

References

Shi S, et al. Mitochondrial Dysfunction: An Emerging Link in the Pathophysiology of Heart Failure and Chronic Kidney Disease. 2022;

Amador-Martínez I, et al. Mitochondrial quality control and stress signaling pathways in cardiorenal diseases. 2025

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Published

2025-09-23

How to Cite

Ali Saqlain Haider, Reja Akram, Irfana Hassan, Muhammad Ahmad Raza Butt, Yamna Fatima, Khadija Kiran. (2025). Mitochondrial Dynamics and Oxidative Stress-Driven Apoptosis: Cardiovascular and renal Implications from an In Vitro Study . International Journal of Pharmacy Research & Technology (IJPRT), 15(2), 2120–2127. Retrieved from https://ijprt.org/index.php/pub/article/view/1020