A Cross-Sectional Study to Assess the Prevalence of Non-Alcoholic Fatty Liver Disease among Type 2 Diabetes Patients

Abstract

Background: Non-alcoholic Liver Disease (NAFLD) is a condition in which fat builds up in the liver of people who drink little or no alcohol. The present study was conducted to assess non alcoholic liver disease in type II diabetes mellitus patients.

Materials & Methods:150 type II diabetes mellitus patients of both genders were divided into 2 groups. Group I had NAFLD, while group II did not. The following measurements were taken as part of a general physical examination: height, weight, waist circumference (WC), hip circumference, and body mass index (BMI). A common mercury manometer was used to measure the systolic and diastolic blood pressure. Venous blood was drawn following an overnight fast of at least eight hours. FBG, serum bilirubin, serum glutamic-oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), alkaline phosphate (ALP), serum total proteins (STP), and lipid profile were all tested using standard laboratory procedures.

Results: Group I had 35 males and 40 females and group II had 30 males and 45 females. The mean BMI (kg/m2) was 23.2±3.1 and 20.3±8.5, waist to hip ratio was 0.90±0.2 and 0.94±0.6, FBG (mg%) was 152.4±25.4 and 144.6±19.7, TC (mg%) was 224.4±15.6 and 194.2±21.3, TGL (mg%) was 215.4±34.5 and 178.4±11.2, HDL (mg%) was 45.5±7.3 and 49.2±8.3, SGOT (IU/L) was 22.1±3.7 and 18.5±1.2, SGPT (IU/L) was 23.3±2.5 and 17.3±3.6, ALP (IU/L) was 125.4±15.5 and 112.7±17.2 and STP (G%) was 6.7±1.0 and 6.1±1.1 and serum bilirubin (mg%) was 0.82±0.1 and 0.80±0.4 in group I and group II respectively. The difference was significant (P< 0.05).

Conclusion: NAFLD is common in patients with type 2 diabetes, and risk factors include obesity, dyslipidemia, and poor glycaemic control.