A Review: Mucoadhesive microspheres a promising tool in drug delivery system

Abstract

Mucoadhesive drug delivery systems promise numerous interests which occur from centralization at a specified objective site, extended dwelling time on the point of preparation absorption and an increased connection to the mucosa rising the drug absorption gradient. Mucoadhesive drug delivery system (MDDS) can be considered to manage drug release and to facilitate prolonged drug maintenance at the site of application. Conventionally typical adhesive materials used in mucoadhesive drug delivery systems generally are the family of hydrogels, such as natural gums, polyacrylates, and cellulose ethers. MDDS is a branch of a controlled delivery system that could be formed to regulate the drug release and to facilitate prolonged drug preservation by the site of application, which accordingly promotes therapeutic efficacy. The commonly essential adhesive materials used in the MDDS typically are the family of hydrogels, such as natural gums, polyacrylates, and polymers.