Efficacy of Platelet-Rich Plasma Vs Corticosteroid Injection in Biceps Tendinitis: A Prospective Comparative Study

Abstract

Introduction: Biceps tendinitis is a common cause of anterior shoulder pain. Corticosteroids provide short-term relief but may impair tendon healing. Platelet-rich plasma (PRP), rich in growth factors, offers a regenerative alternative.

Objective: To compare the efficacy of PRP versus corticosteroid injections in managing biceps tendinitis over 12 weeks.

Methods: A prospective comparative study was conducted on 40 patients diagnosed with biceps tendinitis. Participants received either PRP (n=20) or corticosteroid (n=20) injections under ultrasound guidance. Pain, function, and mobility were assessed using the Visual Analog Scale (VAS), Shoulder Pain and Disability Index (SPADI), and Range of Motion (ROM) at 0, 4, 8, and 12 weeks.

Results: Both groups showed significant improvement in all parameters. At 12 weeks, PRP group had significantly lower VAS scores (1.15 vs. 2.45, p < 0.001) and higher ROM (138.9° vs. 130.15°, p = 0.02). SPADI scores were comparable between groups. Conclusion: PRP provided superior pain relief and mobility improvement compared to corticosteroids. PRP, being autologous and regenerative, is a promising option for long-term management of biceps tendinitis.