Seroepidemological Study of Dengue Fever in Vasantrao Naik Gmc Yavatmal

Abstract

Background: Dengue fever (DF) is a mosquito-borne zoonotic disease that affects humans and non-human primates. The disease is caused by the dengue virus (DENV) which is known to have four distinct serotypes (DENV-1-4) and belongs to the family Flaviviridae, which also includes chikungunya, yellow fever, and Zika viruses. Each of these viruses is known to be transmitted by the female mosquitoes mainly of the species Aedes aegypti and, to a lesser extent, A. albopictus, which become vectors for viral transmission after taking a blood meal from an infected host.

Aim and Objectives: 1. Seroepidemological study of dengue fever in Vasantrao Naik GMC Yavatmal .2. To find out prevalence of dengue infection patients by serological test

Methods: Study Design: Cross sectional study. Study Population: All dengue suspected patients admitted in Vasantrao Naik GMC Yavatmal during study period such cases were included in the study. Study Duration: 2024-2025 Sample size: 1705

Results: Most of the cases found in 12-25 years age group 498 (29.20%) followed by 26-40 group 393 (23.04%), 41-45 age group 294 (17.24%), 56-65 age group 254 (14.90%) and above 66 years age 266 (15.60%). majority of cases were males 1022 (59.94%) and females were 683 (40.05%). most of the cases place of residence was urban area 1270 (74.48%) and 435 cases from rural area (25.51%). Anti-DENV IgM positivity rate was 2.99%, Anti-DENV IgG positivity rate was 3.81%. The entire weighted seroprevalence of dengue-specific antibodies (IgM and/or IgG) in the population studied was 6.8%.

Conclusions: Most of the cases found in 12-25 years age group, majority of cases were males, most of cases from urban area, seroprevalence of NS1 was 1.87%. Anti-DENV IgM positivity rate was 2.99%, Anti-DENV IgG positivity rate was 3.81%. The entire weighted seroprevalence of dengue-specific antibodies (IgM and/or IgG) in the population studied was 6.8%.