Structural Changes in Alveolar Walls in Chronic Smokers and Serum  Surfactant Protein A Levels

Saira Aslam, Ahmad Farzad Qureshi, Nadia Haq, Kanwal Khalid, Muhammad Amjad Bari, Kalsoom Akhter

Structural Changes in Alveolar Walls in Chronic Smokers and Serum Surfactant Protein A Levels

Authors

Saira Aslam, Ahmad Farzad Qureshi, Nadia Haq, Kanwal Khalid, Muhammad Amjad Bari, Kalsoom Akhter

Keywords:

alveolar structure; surfactant protein A; smoking.

Abstract

This prospective cross-sectional study examined structural alterations of alveolar walls and serumsurfactant protein A (SP-A) levels in chronic cigarette smokers compared with matched nonsmoking controls. The objective was to quantify alveolar septal thickening, emphysematous changes and correlate these with circulating

References

Honda Y, Takahashi H, Kuroki Y, Abe S. Decreased contents of surfactant proteins A and D in BAL fluids of healthy smokers. Chest. 1996;109(4):1006–1009. (PubMed)

Kida K, Oda H, Yamano Y, Kagawa J. Effects of cigarette smoking on the serum concentration of lung surfactant protein A. Eur Respir J. 1997;10(10):2124–2126. (PMC)

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Published

2025-09-23

How to Cite

Saira Aslam, Ahmad Farzad Qureshi, Nadia Haq, Kanwal Khalid, Muhammad Amjad Bari, Kalsoom Akhter. (2025). Structural Changes in Alveolar Walls in Chronic Smokers and Serum Surfactant Protein A Levels . International Journal of Pharmacy Research & Technology (IJPRT), 15(2), 2167–2173. Retrieved from https://ijprt.org/index.php/pub/article/view/1027