A Review on compatibility of “Sucralfate” in bi layer floating tablet for treatment of ulcer in pregnancy.

SREEDHAR RANJAN DAS; Dr BIBHUTI BHUSANPANIGRAHI; Dr MANOJKUMAR PANI

doi:10.31838/ijprt/10.01.04

Authors

SREEDHAR RANJAN DAS Department of Pharmaceutics, Indira Gandhi Institute of Pharmaceutical Sciences, Bhubaneswar.
Dr BIBHUTI BHUSANPANIGRAHI Department of Pharmaceutics, Indira Gandhi Institute of Pharmaceutical Sciences, Bhubaneswar.
Dr MANOJKUMAR PANI Department of Pharmaceutics, Indira Gandhi Institute of Pharmaceutical Sciences, Bhubaneswar. *Corresponding Author

DOI:

https://doi.org/10.31838/ijprt/10.01.04

Keywords:

Sucralfate, Ulcerprotective, Bilayered floating tablet, GRDDS

Abstract

To make a review by focusing upon characteristics of Sucralfate and its compatibility in Bilayer floating tablet for treatment of ulcer during pregnancy as Gastro Retaintive Drug Delivery System. This review focus on causes of stomach ulceration during pregnancy, characteristics study of Sucralfate and its compatibility with acceptance criterias of Bilayer Floating Tablet for treatment of ulceration during pregnancy .The ulcer protective Sucralfare is simpler and more effective H2 blockers. They can be implemented in case of pregnancy and administrated as combined form in empty stomach .Bi layer floating tablet is an approach of GRDDS. In Bi layered floating tablet ,Sucralfate can act as immediate release layer and absorbs at stomach and improve the bioavailability and which ideal dosage form attains the desired therapeutic concentration of drug in plasma and maintains constant frequency for entire duration of treatment.