Study of Nerve Conduction Velocity in Normal Subject Having Parental History of Diabetus Mellitus

Abstract

ABSTRACT: Background: Diabetes Mellitus (DM) is defined as a metabolic abnormality characterized by hyperglycaemia and disturbances of carbohydrate, fat and protein metabolism that are associated with absolute or relative deficiency in insulin secretion and/or insulin action. When fully evolved, it is characterized by fasting hyperglycaemia but it can also be characterized in the less overt stages and before fasting hyperglycaemia appears, most usually by the appearance of glucose intolerance.

Aim and Objectives:1. To evaluate nerve conduction in off-springs of diabetic and non-diabetic parents.2.To study BMI in off-springs of diabetic parents.

Methodology: Present study was a cross sectional study done at Department of Physiology, Grant Government Medical College Mumbai during a period of December 2014 to October 2016. The study involved randomly selected 100 students of first year MBBS students, these can be divided in two groups (50 study groups and 50 Control groups) depending on family history of diabetes mellitus and children with parents having diabetes mellitus were taken as study group.

Result: The study groups were comparable in terms of age and other physical parameters. There was no significant difference in mean ± S.D. of height, weight, Body mass index (BMI) between study group and controls but there was significant decreased in nerve conduction velocity in study group.

Conclusion: We find that neuropathy can be started at early age in study groups.