Neuroprotective Effects of Αlpha-Tocopherol and Naringenin Against  Amyloid-β (1-42)- Induced Neurotoxicity in SH-SY5Y Cells

Chanchal Yadav, Nalini Kanta Sahoo

Neuroprotective Effects of Αlpha-Tocopherol and Naringenin Against Amyloid-β (1-42)- Induced Neurotoxicity in SH-SY5Y Cells

Authors

Chanchal Yadav, Nalini Kanta Sahoo

Keywords:

Amyloid-β, Neuroprotection, α Tocopherol, Antioxidant, Naringenin

Abstract

Oxidative stress plays a central role inamyloid-β (Aβ)-mediated neurotoxicity andthe progression of Alzheimer's disease.Targeting oxidative damage usingantioxidant compounds has emerged as a promising therapeutic strategy.

References

Selkoe DJ, Hardy J. The amyloid hypothesis of Alzheimer's disease at 25 years. EMBO Mol Med. 2016 Jun 1;8(6):595-608. doi:10.15252/emmm.201606210. PMID: 27025652; PMCID: PMC4888851.

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Published

2025-12-25

How to Cite

Chanchal Yadav, Nalini Kanta Sahoo. (2025). Neuroprotective Effects of Αlpha-Tocopherol and Naringenin Against Amyloid-β (1-42)- Induced Neurotoxicity in SH-SY5Y Cells . International Journal of Pharmacy Research & Technology (IJPRT), 15(2), 4665–4676. Retrieved from https://ijprt.org/index.php/pub/article/view/1676