Dual-Loaded Niosomal Delivery of Tea Tree Oil and Adapalene: Formulation Optimization and Physicochemical Characterization
Keywords:
Niosomes co loaded; Tea tree oil; Adapalene; Delivery of drug Topical Type of drug Entrapment efficiency Response surface methodology Nanocarriers Acne treatment Controlled drug release Vesicular drug delivery system.Abstract
In the present ethical neuronalpresymptomatic Ԁetection (End) study, we intend toformulate and evaluate co-encapsulated adapalene(ADP) and tea tree oil (TTO) in niosomes for effectiveanti-acne therapy with minimized side effects.Niosomes were prepared using thin film hydrationtechnique and characterized by factorial design todetermine the effect of formulation variables (Span 60and cholesterol) on the characteristics of the vesicles.
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