Prognostic Value of Serum Lactate Levels in Predicting Outcomes in  Perforated Duodenal Ulcer: A Retrospective Observational Cohort Study

Suhail Abbas, Awhad Mueed Yousuf , Hashmat Shameem Rather, Arshad Rashid

Prognostic Value of Serum Lactate Levels in Predicting Outcomes in Perforated Duodenal Ulcer: A Retrospective Observational Cohort Study

Authors

Suhail Abbas, Awhad Mueed Yousuf , Hashmat Shameem Rather, Arshad Rashid

Keywords:

perforated duodenal ulcer; serum lactate; lactate clearance; mortality; risk stratification

Abstract

Background. Perforated duodenal ulcer (PDU) carries a mortality of up to 30%. Serum lactate is a rapid, inexpensive marker of tissue hypoperfusion. We assessed its value in predicting outcome after PDU repair.

References

1.Søreide K, Thorsen K, Harrison EM, Bingener J, Møller MH, Ohene-Yeboah M, et al. Perforated peptic ulcer. Lancet. 2015;386(10000):1288–98.

2.Tarasconi A, Coccolini F, Biffl WL, Tomasoni M, Ansaloni L, Picetti E, et al. Perforated and bleeding peptic ulcer: WSES guidelines. World J Emerg Surg. 2020;15:3

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Published

2026-07-29

How to Cite

Suhail Abbas, Awhad Mueed Yousuf , Hashmat Shameem Rather, Arshad Rashid. (2026). Prognostic Value of Serum Lactate Levels in Predicting Outcomes in Perforated Duodenal Ulcer: A Retrospective Observational Cohort Study. International Journal of Pharmacy Research & Technology (IJPRT), 16(2), 1351–1358. Retrieved from https://ijprt.org/index.php/pub/article/view/2520