Prevalence of Helicobacter pylori Infection in Gastro-Duodenal  Perforation and Its Clinical Implications: A Prospective Observational  Study

Dr K. Nithya, Dr K. Gokul, Dr R. Stalin

Prevalence of Helicobacter pylori Infection in Gastro-Duodenal Perforation and Its Clinical Implications: A Prospective Observational Study

Authors

Dr K. Nithya, Dr K. Gokul, Dr R. Stalin

Keywords:

Helicobacter pylori; Gastro duodenal perforation; Peptic ulcer disease; Rapid urease test; Duodenal ulcer; Eradication therapy.

Abstract

Background: Gastro-duodenal perforationis a surgical emergency with high morbidity and mortality, and peptic ulcer disease—
frequently linked to Helicobacter pylori infection—is a common underlying cause. The role of H. pylori and the need for
eradication therapy in perforation cases remain incompletely defined

References

1. Irvin TT. Mortality and perforated peptic ulcer: a case for risk stratification in elderly patients. Br J Surg. 1989;76:215–8.

2. Zittel TT, Jehle EC, Becker HD. Surgical management of peptic ulcer disease today—indication, technique and outcome. Langenbecks Arch Surg. 2000;385:34–96.

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Published

2026-02-25

How to Cite

Dr K. Nithya, Dr K. Gokul, Dr R. Stalin. (2026). Prevalence of Helicobacter pylori Infection in Gastro-Duodenal Perforation and Its Clinical Implications: A Prospective Observational Study. International Journal of Pharmacy Research & Technology (IJPRT), 16(1), 5454–5460. Retrieved from https://ijprt.org/index.php/pub/article/view/2821