A Preliminary Investigation of Moringa Oleifera Lam Gum As a Pharmaceutical Excipient

Dhiren P Shah; Vineet C Jain; Hitesh P Daldavi; Vinod D Ramani; Kajal G Patel; Mahesh G Saralai; Girish K Jani

doi:10.31838/ijprt/01.01.03

Authors

Dhiren P Shah C K Pithawalla Institute of Pharmaceutical Science and Research, Via Magdalla Port, Nr. Malvan Mandir, Dumas Road, Gavior Gam, Surat – 395 007.,
Vineet C Jain C K Pithawalla Institute of Pharmaceutical Science and Research, Via Magdalla Port, Nr. Malvan Mandir, Dumas Road, Gavior Gam, Surat – 395 007.
Hitesh P Daldavi C K Pithawalla Institute of Pharmaceutical Science and Research, Via Magdalla Port, Nr. Malvan Mandir, Dumas Road, Gavior Gam, Surat – 395 007.,
Vinod D Ramani C K Pithawalla Institute of Pharmaceutical Science and Research, Via Magdalla Port, Nr. Malvan Mandir, Dumas Road, Gavior Gam, Surat – 395 007.
Kajal G Patel C K Pithawalla Institute of Pharmaceutical Science and Research, Via Magdalla Port, Nr. Malvan Mandir, Dumas Road, Gavior Gam, Surat – 395 007.
Mahesh G Saralai C K Pithawalla Institute of Pharmaceutical Science and Research, Via Magdalla Port, Nr. Malvan Mandir, Dumas Road, Gavior Gam, Surat – 395 007.
Girish K Jani S S R College of Pharmacy, Silvassa - Sayli Road, Silvassa, U T of D & NH – 396 230.

DOI:

https://doi.org/10.31838/ijprt/01.01.03

Keywords:

Aceclofenac, Moringa oleifera Lam, Natural Excipient

Abstract

Mother nature has gifted India with great variety of flora and fauna. Since centuries man has made an effective use of material from natural origins in the medical & pharmaceutical field. In present study, Moringa oleifera Lam., was explored as a pharmaceutical excipient. Various physico-chemical properties like particle size, solubility, swelling ratio, flow property and compressibility were measured and compared with other materials also. Aceclofenac tablets containing Moringa were prepared and evaluated for various quality control parameters like hardness, friability, wetting time and disintegration time. Drug releases from Aceclofenac tablets were performed. Finally, stability study of optimized batch was carried out. It was observed that Moringa gum had excellent swelling ratio, flow property and compressibility. Batch F3 was considered as optimized batch due to lesser disintegration time, hardness & friability are within the limit. Tablets are stable after stability study.