Influence of Smoking on Post-Tuberculosis Lung Function and Functional Exercise Capacity: A Comparative Study

Abstract

Aim/Objectives: To compare the respiratory function 6 min walk test, spirometry (overall functional status) among the treated pulmonary tuberculosis patients with sequelae among smokers and non-smokers.

Materials and Methods: A prospective study of 100 post TB Patients was carried out in the Department of Respiratory Medicine, Chalmeda Anand Rao Medical Sciences, Karimnagar after the approval from the Ethical Committee of the CAIMS.

Results: In this study of 100 post-tuberculosis patients (mean age 51 years), smokers (45%) demonstrated more severe clinical, radiological, and functional impairment than non-smokers. Mixed ventilatory defects were predominant among smokers and were significantly associated with worse spirometry (P < 0.0001). Smoking index showed a strong negative correlation with lung function and 6MWT distance. Smokers had reduced exercise capacity and greater bilateral lung involvement compared to non-smokers

Conclusion: Post-tuberculosis patients who smoke show greater reductions in spirometry                                              values and six-minute walk distance compared to non-smokers. Spirometry and six- minute walk tests help assess functional status and quality of life. These tests guide rehabilitation planning to reduce symptoms and improve function. Smoking cessation must be strongly encouraged in all tuberculosis patients.