Green Synthesis of Silver Nanoparticles by Using Tinospora Cordifolia Stem Powder, Characterization and Its Antibacterial Activity Against Antibiotics Resistant Bacteria

Abstract

Silver nanoparticles were synthesized from 1mM aqueous silver nitrate through an ecofriendly and cost effective method by using Tinospora cordifolia stem powder. The bioreduction behavior of stem powder of Tinospora cordifolia is responsible for this biosynthesis. The stem powder extracts mixed with silver nitrate showed gradual change in the color of the extracts from yellow to dark brown. The formation of silver nanoparticles was confirmed by UV-Visible spectrophotometer, X-Ray diffraction (XRD), Fourier transform infrared (FTIR), Energy dispersive spectroscopy (EDAX) and Transmission electron microscopy (TEM). Silver nanoparticles have been known to have bactericidal and inhibitory effects. Resistance to antibiotics by pathogenic bacteria has emerged in recent years and is a major health problem. The effects of silver nanoparticles and different antibiotics on antibiotic resistant bacteria have not been studied.