CARBOPLATIN INDUCED ISCHEMIC OPTIC NEUROPATHY

Dr. Nitin Mehrotra, Dr. Rachit Rastogi, Dr. G.S. Titiyal

CARBOPLATIN INDUCED ISCHEMIC OPTIC NEUROPATHY

Authors

Dr. Nitin Mehrotra, Dr. Rachit Rastogi, Dr. G.S. Titiyal

Keywords:

Carboplatin, Optic Neuropathy, Field defects, Anticancer agents.

Abstract

Cisplatin and carboplatin are the two platinum based alkylating agents usedwidely as anti-cancer therapy. Carboplatin is more chemically stable and better tolerated withcomparatively favourable profile. Reports of Carboplatin precipitating optic neuropathy israrely reported.

References

Dulz S, Asselborn NH, Dieckmann KP, et al.: Retinal toxicity after cisplatin-based chemotherapy in patients with germ cell cancer. J Cancer Res ClinOncol.2017, 143:1319-25. 10.1007/s00432-017-2384-8

Polat N, Ciftci O, Cetin A, Yılmaz T: Toxic effects of systemic cisplatin on rat eyes and the protective effect of hesperidin against this toxicity. CutanOculToxicol. 2016, 35:1-7. 10.3109/15569527.2014.999080

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Published

2025-08-04

How to Cite

Dr. Nitin Mehrotra, Dr. Rachit Rastogi, Dr. G.S. Titiyal. (2025). CARBOPLATIN INDUCED ISCHEMIC OPTIC NEUROPATHY . International Journal of Pharmacy Research & Technology (IJPRT), 15(2), 942–948. Retrieved from https://ijprt.org/index.php/pub/article/view/816