Role of Contrast-Enhanced CT and Serum Alpha-Fetoprotein in Early  Detection of Hepatocellular Carcinoma

Naeem Ahmad Khan, Beenish Javaid, Fatima Iqbal, Nazish Khalid, Attka Maryam, Muhammad Ahmad Raza Butt

Role of Contrast-Enhanced CT and Serum Alpha-Fetoprotein in Early Detection of Hepatocellular Carcinoma

Authors

Naeem Ahmad Khan, Beenish Javaid, Fatima Iqbal, Nazish Khalid, Attka Maryam, Muhammad Ahmad Raza Butt

Keywords:

Hepatocellular carcinoma, contrast-enhanced CT, alpha-fetoprotein, early detection, diagnostic accuracy

Abstract

Early detection of hepatocellular carcinoma (HCC) remains a global challenge due to itsasymptomatic course and high mortality. Serum alpha-fetoprotein (AFP) is widely used insurveillance but suffers from limited sensitivity and specificity, especially for small lesions. Contrast-enhanced computed tomography

References

Kim H, Park J. Advances in imaging for hepatocellular carcinoma surveillance. Hepatology. 2022;76(3):859–870. DOI: https://doi.org/10.1002/hep.32341

Yang JD, Heimbach JK. New developments in the diagnosis and management of HCC. Hepatology. 2023;77(4):1214–1226. DOI: https://doi.org/10.1002/hep.32899

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Published

2025-09-22

How to Cite

Naeem Ahmad Khan, Beenish Javaid, Fatima Iqbal, Nazish Khalid, Attka Maryam, Muhammad Ahmad Raza Butt. (2025). Role of Contrast-Enhanced CT and Serum Alpha-Fetoprotein in Early Detection of Hepatocellular Carcinoma . International Journal of Pharmacy Research & Technology (IJPRT), 15(2), 2037–2043. Retrieved from https://ijprt.org/index.php/pub/article/view/1008