Comparative Evaluation of Single-Dose Intravenous vs. Dual-Route  (Intravenous and Peri-articular) Tranexamic Acid in Total Knee Arthroplasty:  A Randomized controlled trial study in a Tertiary Orthopaedic Centre

Dr Praveen Kumar Chavan, Dr Avinash Parthasarthy, Dr R C Karthik

Comparative Evaluation of Single-Dose Intravenous vs. Dual-Route (Intravenous and Peri-articular) Tranexamic Acid in Total Knee Arthroplasty: A Randomized controlled trial study in a Tertiary Orthopaedic Centre

Authors

Dr Praveen Kumar Chavan, Dr Avinash Parthasarthy, Dr R C Karthik

Keywords:

Abstract

Background: Minimizing perioperativehaemorrhage is critical for enhancingrecovery after total knee arthroplasty (TKA). While the efficacy of Tranexamic Acid(TXA) is well-documented, the clinicaladvantage of augmenting systemicadministration with local joint infiltration

References

GBD 2021 Osteoarthritis Collaborators. Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021. Lancet Rheumatol. 2023;5(9):e508-22

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Published

2026-02-16

How to Cite

Dr Praveen Kumar Chavan, Dr Avinash Parthasarthy, Dr R C Karthik. (2026). Comparative Evaluation of Single-Dose Intravenous vs. Dual-Route (Intravenous and Peri-articular) Tranexamic Acid in Total Knee Arthroplasty: A Randomized controlled trial study in a Tertiary Orthopaedic Centre. International Journal of Pharmacy Research & Technology (IJPRT), 16(1), 542–551. Retrieved from https://ijprt.org/index.php/pub/article/view/1531