Preparation and Evaluation of Diclofenac Suspension by using Trigonella Foenum Graecum Mucilage as suspending agent

Abstract

The purpose to perform this is to study is to prepare and evaluate a novel and effective suspending agent from natural source that can be utilized as a better alternative for traditional suspending agent. In the first step the extraction of mucilage as a suspending agent from theseeds of Trigonella foenum graecum followed by steps involving testing of the mucilage obtained which include solubility testing, phytochemical testing, swelling index determination, preparation of diclofenac suspension (blank), sedimentation volume determination, measurement of viscosity, and flow rate determination. The result of study showed that the mucilage extractionof fenugreek seeds had potential as suspending agent. It contains carbohydrates, alkaloids,proteins and amino acid. The fenugreek seeds mucilage as a suspending agent shows highest sedimentation volume as collate with acacia, tragacanth and diclofenac only.