Organophosphorus Poisoning In Pregnancy. A Case Report and Review of Literature

Abstract

Organophosphorus poisoning is a significant public problem specially in developing countries where domestic abuse, poverty and gender inequity is a matter of great concern. Organophosphorus which is present in pesticides is easily accessible in developing countries for homicidal as well as suicidal cases. A case of 26-year-old intubated primi (G1POLO) at 34 weeks gestation presented in emergency with history of domestic fight followed by some pesticide intake 24 hours back.

Patient was intubated at some local hospital due to respiratory depression. There was history of multiple episodes of vomiting, excessive salivation, sweating followed by unconsciousness.

Patient was given Intravenous atropine to reverse the cholinergic side effects. Her plasma pseudocholinesterase levels were also very low (150 lU) which further confirmed the diagnosis. Intravenous infusion atropine dose continued for a duration of 5 days till full recovery was achieved. Patient was discharged in stable condition and delivered vaginally at 37 weeks of gestation. There were no residual neurological defects in fetus as well as mother.