Role of Adipokines (Leptin and Adiponectin) in the  Pathophysiology of Polycystic Ovary Syndrome in Pakistani  Women

Khurram Munir, Beenish Zafar, Fouzia Rahim, Roomisa Anis, Hadiya Sibghatullah, Sidra Latif

Role of Adipokines (Leptin and Adiponectin) in the Pathophysiology of Polycystic Ovary Syndrome in Pakistani Women

Authors

Khurram Munir, Beenish Zafar, Fouzia Rahim, Roomisa Anis, Hadiya Sibghatullah, Sidra Latif

Keywords:

PCOS, leptin, adiponectin, insulin resistance, Pakistan, HOMA-IR

Abstract

Background: Polycystic Ovary Syndrome is a common endocrine disorder among women ofreproductive age, frequently associated with insulin resistance and obesity. Adipokines, particularly leptin and adiponectin, play a key role in linking metabolic and reproductive abnormalities.

References

1. Teede HJ, Misso ML, Costello MF, Dokras A, Laven JSE, Moran LJ, Piltonen T, et al. Recommendations from the international evidence-based guideline for polycystic ovary syndrome. 2023;38(5):1–27. Hum Reprod.

2. Escobar-Morreale HF. Polycystic ovary syndrome: definition and epidemiology Lancet Diabetes Endocrinol.2022;10(9):668–680.

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Published

2026-05-13

How to Cite

Khurram Munir, Beenish Zafar, Fouzia Rahim, Roomisa Anis, Hadiya Sibghatullah, Sidra Latif. (2026). Role of Adipokines (Leptin and Adiponectin) in the Pathophysiology of Polycystic Ovary Syndrome in Pakistani Women. International Journal of Pharmacy Research & Technology (IJPRT), 16(1), 2524–2527. Retrieved from https://ijprt.org/index.php/pub/article/view/1909