Association of NSAID Exposure, Stone Burden and Metabolic Abnormalities  With Reduced Renal Function in Patients With Recurrent Urolithiasis: A  Cross-Sectional Analytical Study

Irfan Elahi, Zainab Mustafa, Irfan Ahmad, Abdul Razaq, Hafsa Siddiqui, Fouzia Perveen

Association of NSAID Exposure, Stone Burden and Metabolic Abnormalities With Reduced Renal Function in Patients With Recurrent Urolithiasis: A Cross-Sectional Analytical Study

Authors

Irfan Elahi, Zainab Mustafa, Irfan Ahmad, Abdul Razaq, Hafsa Siddiqui, Fouzia Perveen

Keywords:

Urolithiasis, NSAID exposure, nephrotoxicity, chronic kidney disease, metabolic stone screening, hyperoxaluria, stone burden

Abstract

Recurrent urolithiasis causes progressive renal parenchymal injury through obstructive uropathy,repeated surgical interventions, underlying metabolic derangements, and frequent exposure to nonsteroidal anti-inflammatory drugs (NSAIDs) for acute renal colic management. The objective of this cross-sectional analytical study

References

1. Rule, A. D., Krambeck, A. E., & Lieske, J. C. (2011). Chronic kidney disease in kidney stone formers. Clinical Journal of the American Society of Nephrology, 6(8), 2069–2075.

2. Sorokin, I., Mamoulakis, C., Miyazawa, K., Rodgers, A., Talati, J., & Lotan, Y. (2017). Epidemiology of stone disease across the world. World Journal of Urology, 35(9), 1301–1310.

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Published

2026-09-10

How to Cite

Irfan Elahi, Zainab Mustafa, Irfan Ahmad, Abdul Razaq, Hafsa Siddiqui, Fouzia Perveen. (2026). Association of NSAID Exposure, Stone Burden and Metabolic Abnormalities With Reduced Renal Function in Patients With Recurrent Urolithiasis: A Cross-Sectional Analytical Study . International Journal of Pharmacy Research & Technology (IJPRT), 16(2), 4591–4602. Retrieved from https://ijprt.org/index.php/pub/article/view/3069