Histomorphological Evaluation of the Sciatic Nerve in Diabetic Neuropathy  and Its Correlation with HbA1c Levels

Mehreen Salahuddin, Kanwal Sharif, Javeria Noor, Saba Saleem, Zubda Akhtar, Shazia Gul

Histomorphological Evaluation of the Sciatic Nerve in Diabetic Neuropathy and Its Correlation with HbA1c Levels

Authors

Mehreen Salahuddin, Kanwal Sharif, Javeria Noor, Saba Saleem, Zubda Akhtar, Shazia Gul

Keywords:

Diabetic peripheral neuropathy; Sciatic nerve; Histomorphometry; Glycated hemoglobin; HbA1c; Myelinated fiberdensity;Segmental demyelination;Microangiopathy.

Abstract

Background: Diabetic peripheral neuropathy(DPN) is among the most frequent anddisabling long-term microvascular complications of diabetes mellitus. Whileclinical evaluation and nerve conduction

References

1. Maintain target HbA1c levels below 7.0 percent in diabetic patients to reduce endoneurial microvascular basement membrane

thickening and prevent myelinated fiber loss

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Published

2026-11-04

How to Cite

Mehreen Salahuddin, Kanwal Sharif, Javeria Noor, Saba Saleem, Zubda Akhtar, Shazia Gul. (2026). Histomorphological Evaluation of the Sciatic Nerve in Diabetic Neuropathy and Its Correlation with HbA1c Levels . International Journal of Pharmacy Research & Technology (IJPRT), 16(2), 7716–7733. Retrieved from https://ijprt.org/index.php/pub/article/view/3525