Effect of Arogyavardhini Vati on Serum Low-Density Lipoprotein Levels: A Prospective Interventional Study
Keywords:
Arogyavardhini Vati, Dyslipidemia, Ldl Cholesterol, Ayurveda, Cardiovascular Risk.Abstract
Background: Dyslipidemia, particularly elevated low-density lipoprotein (LDL) cholesterol, is a major risk factor for cardiovascular morbidity and mortality [1, 2]. Lifestyle factors, metabolic stress, and chronic inflammation contribute significantly to abnormal lipid profiles [3]. Arogyavardhini Vati, a classical Ayurvedic formulation, is traditionally used for metabolic regulation, liver disorders, and lipid abnormalities [4]. However, limited clinical evidence exists regarding its effect on serum LDL levels.
Aim: To evaluate the effect of Arogyavardhini Vati on serum low-density lipoprotein (LDL) levels.
Methodology: This prospective interventional study included 50 consenting subjects with elevated serum LDL levels. Serum LDL concentrations were measured at baseline and after 6 months of Arogyavardhini Vati administration. Statistical analysis was performed using paired t-test.
Results: There was a statistically significant reduction in serum LDL levels after 6 months of intervention (p < 0.001). Mean LDL levels decreased from 188.58 ± 14.42 mg/dl at baseline to 97.76 ± 22.94 mg/dl at follow-up. At baseline, all subjects had elevated LDL levels, whereas at follow-up, 90% achieved LDL values within the normal range.
Conclusion: Arogyavardhini Vati resulted in significant reduction in serum LDL levels, suggesting its potential role as an effective therapeutic option in the management of dyslipidemia.
